Cialis
Cialis is one of the most popular drugs for 2023 used in the treatment of potency disorders in men of all ages. Cialis is an oral medication that comes in the form of film-coated tablets. According to the pharmacological classification, Cialis belongs to the PDE-5 inhibitors. Regardless of the active substance (4 names are currently registered), PDE-5 inhibitors contribute to the accumulation of cGMP inside the smooth muscle cavernous cells, as well as in the cells of the smooth muscle layer of the arteries of the penis. Relaxation of smooth muscle cells increases the flow of arterial blood to the cavernous bodies, resulting in a stronger and longer erection. The principle of action of all these drugs is the same. In order for them to have an effect, it is necessary for the man to experience sexual desire or sexual stimulation. If this condition is not met, arousal doesn’t occur, since PDE-5 inhibitors don’t affect libido and are not aphrodisiacs.
Erectile Dysfunction Medication
As follows from the specification of Cialis, this drug is primarily used in the treatment of erectile dysfunction – a violation of potency, in which a man has difficulty achieving and maintaining an erection sufficient to obtain satisfaction from a fully completed sexual intercourse. However, in addition to this, Cialis is also used in the treatment of a disease such as benign prostatic hyperplasia. BPH, also known as BPH, occurs in more than 60% of men over 55 years of age. Most men with severe benign prostatic hyperplasia have difficulty achieving and maintaining an erection and suffer from extremely uncomfortable lower urinary tract symptoms (LUTS). It is noteworthy that of all the drugs from the category of PDE-5 inhibitors, which is used in the treatment of symptoms of erectile dysfunction, only Cialis is intended and approved for use in patients with benign prostatic hyperplasia. This makes this medicine a truly unique tool in the fight against potency disorders in older men.
Cialis was registered and approved by the FDA for use as a treatment for erectile dysfunction back in 2003, and only in 2012 received approval as a drug that can be used in the treatment of benign prostatic hyperplasia. This marked a sort of renaissance of Cialis. The popularity of this drug has greatly increased due to the fact that urologists began to recommend it to aged patients, among whose complaints there are both erectile dysfunction and problems with the prostate gland.
Over the 20 years of its existence, Cialis has successfully proved that it is a means to restore potency, in no way inferior to the famous pioneer in the field of combating erectile dysfunction – Viagra. Moreover, this medicine has a number of advantages over the pioneer, namely, better tolerance by the body, a much longer action (after taking the pill, it remains in the system up to 36 hours), the possibility of taking with BPH, fewer and more severe side effects. Many end users are also pleased that Cialis can be combined with a small amount of alcohol, and the amount of food eaten practically does not affect the rate of its absorption and the strength of its effect on the body.
Cialis is successfully used in the treatment of erectile dysfunction of both physiological and psychological etiology, as well as mixed etiology. It is the cases of ED of mixed etiology that are most frequent in medical practice. This is due to the fact that often the presence of certain physiological prerequisites for potency disorders, even if they are not very serious, makes a man be in a state of anxiety and stress, as a result of which his potency worsens even more. And vice versa, when stress is at the very basis of the problem with potency, this state of the body invariably entails the emergence of objective physiological problems. Being a safe and modern medicine, Cialis helps to cope with all these problems and return to the joys of a fulfilling sexual life.
Cialis is based on the active substance Tadalafil. If we talk about other PDE-5 inhibitors, then in addition to the well-known Viagra, the active ingredient of which is Sildenafil citrate, on the modern pharmaceutical market there is also Levitra, the active ingredient of which is Vardenafil, and the much less well-known drug Stendra with the active ingredient Avanafil.
Prescription Drugs
By default, all drugs in the PDE-5 inhibitor category are prescription drugs. Nevertheless, it should be noted that this requirement for dispensing drugs from pharmacies is most strictly observed in the United States and some EU countries, mainly Western European ones. In other countries, even in Europe, the attitude to this issue is much more liberal. But the consumer will get the least trouble when buying a medicine to combat erectile dysfunction from the countries of the South Asian region, primarily from India. It is here that up to 95% of the total market for generic PDE-5 inhibitors is produced.
Online Pharmacies
Speaking about the receptor status of PDE-5 inhibitors, it is impossible not to mention online pharmacies. It is no secret that, despite the fact that they are subject to the same legal requirements as offline pharmacies, it is much easier to buy any medicine without a prescription on the Internet. This is most likely due to the fact that it is extremely difficult for regulators to verify whether a pharmacy representative has actually verified that a customer has a prescription for a particular drug. Indeed, unlike a typical offline pharmacy, where everything is clearly visible in numerous stone drops, it is hundreds of times more difficult to track the actions of a site visitor. Thanks to this, even in some American pharmacies, if you try very hard, you can buy Cialis without a prescription. However, we would advise our readers not to go to great lengths and waste their time looking for a similar online pharmacy based in the USA. It is much easier to buy Cialis, Viagra or Levitra without a prescription using the services of foreign online pharmacies. By placing an order, for example, in an Indian online pharmacy directly from the supplier, you will not only receive the desired drugs without the coveted paperwork from the doctor, but also save significant amounts of money, since the vast majority of the range is represented by generics. However, if this is a matter of principle for you, you can also buy the original (branded) medicine.
Generic Medication
Since we are talking about generics, we consider it our duty to explain what they are and what is the difference between generics and original drugs.
The discussion of what is the difference between branded drugs and their copies, that is, generics, has been going on for more than a decade. When a fundamentally new drug appears, the companies that invented it, tested its action in various clinical trials and became its first manufacturer, are granted a patent. It is valid for a certain period of time, usually 20 years, less often 15 or 18, when no other companies can produce drugs with the same active ingredient. Thus, the inventing company receives the sole right to manufacture a branded drug, which in most cases is sold at a very high price. This is due to the fact that the company must recoup the cost of developing a drug, which often amounts to hundreds of millions of dollars.
A generic is a reproduction of an innovative product whose patent protection has expired. Generic must contain the same active ingredient as its prototype, and usually in the same dosage, but may include other or additional excipients. The cost of generics is almost always much lower than the cost of original drugs, since companies that produce generics don’t bear the cost of developing and testing their products, but use ready-made medicinal formulas.
The issue of “interchangeability” of modern generics of all PDE-5 inhibitors has been proven, and quality standards comply with WHO guidelines. Quite often generics of Cialis and other drugs against erectile dysfunction are produced by fairly well-known companies that produce many of their own original drugs.
Generic Cialis
To date, an increasing number of men who have experienced potency disorders prefer to purchase Cialis generics, which have become available on the pharmaceutical market since 2018, 15 years after the invention of the original drug. Like their prototype, all Cialis generics contain the active ingredient Tadalafil, usually in the same dosages (namely, 5, 10 and 20 mg per tablet). There may be other options, such as 20mg per tablet, but these mean that the tablet should be split in two before taking to avoid overdosing. Among some people, there is still a dismissive and wary attitude towards generics, however, such prejudices are completely unfounded.
WHO requires manufacturers of generics to confirm their biological equivalence, i.e. the content of the active substance and effectiveness equivalent to the original, before launching a drug onto the market. Also, ideally, the manufacturer should confirm the therapeutic and pharmacological equivalence. Most major manufacturers do just that.
Buy Generic Cialis
Modern Cialis generics help to restore potency just as well as the original medicine, and in some cases it is even better tolerated by the body. It is easiest to buy generics in online pharmacies, primarily in foreign national pharmacies, as well as in large international pharmacies. For those consumers who seek to purchase generic Cialis at the best price, but not at the expense of quality, it is best to turn their attention to the Indian analogues of the original medicine. Among them there are many non-standard solutions, such as Cialis in the form of soft tablets or oral gel sachets. Recently, even capsules have appeared. And all this at a price of $1-3 per tablet, which is simply ridiculous compared to the $60-80 that Eli Lilly Corporation requires for one unit of its products. For US residents, the process of buying Cialis generics abroad is more difficult for me than buying any product on Amazon.
